Domains

Domains

Domains are OMOP-defined clinical entity categories that are defined for each Concept in the Standardized Vocabulary. A list of all Domains is stored in the DOMAIN table. In the CONCEPT table, the field domain_id of each Concept record determines the Domain the Concept belongs to.

All Standard and Classification Concepts (standard_concept = 'S' or 'C') have a unique Domain, while the non-standard Source Concepts (standard_concept = NULL) can have domain_id entries that represent combinations of domains.

Domain assignment

Domain assignments are done using a heuristic, which is different for each vocabulary. Most vocabularies have Concepts in one of few Domains, but some of them, like HCPCS or Read, are very broad. The assignment will follow the following logic:

Condition

• Disease
• Clinical finding

Drug

• Drug product
• Vaccine
• Immunization recorded as a procedure

Device

• Medical device
• Contrast media
• Blood product
• Dietary supplement

Measurement

• Measure of an analyte or entity
• Assessment scale

Procedure

• Manual or robotic manipulation on a patient

Observation

• Observational finding
• Observational assessment
• Observable entity

However, for some of the categories, the assignment can be ambiguous. For these cases, in the OMOP Standardized Vocabulary we use the following rules:

Category	Example	Domain
Behavioral abnormality	ICD10CM Z72.810 Child and adolescent antisocial behavior	Condition
Blood bank product	CPT4 86930 Frozen blood, each unit; freezing (includes preparation)	Device
Contrast material for imaging	HCPCS A9581 Injection, gadoxetate disodium, 1 ml	Device
Food Supplement	SPL 304fdee6-0290-4717-be3d-b367bec7e411 Ferrous Gluconate	Device
Graft (alive or artificial)	HCPCS L8670 Vascular graft material, synthetic, implant	Device
Implant (not drug eluding)	HCPCS L8610 Ocular implant	Device
Medical supply	HCPCS A4336 Incontinence supply, urethral insert, any type, each	Device
Nutrition (enteral)	HCPCS B4152 Enteral formula, nutritionally complete, calorically dense (equal to or greater than 1.5 kcal/ml) with intact nutrients, includes proteins, fats, carbohydrates, vitamins and minerals, may include fiber, administered through an enteral feeding tube, 100 cal…	Device
Nutrition (parenteral)	HCPCS B5200 Parenteral nutrition solution: compounded amino acid and carbohydrates with electrolytes, trace elements, and vitamins, including preparation, any strength, stress - branch chain amino acids - premix	Device
Prosthesis	HCPCS L6687 Upper extremity addition, frame type socket, below elbow or wrist disarticulation	Device
Radioactive material for imaging	HCPCS C1204 Technetium tc 99m tilmanocept, diagnostic, up to 0.5 millicuries	Device
Radiological procedure supply, radiopharmaceutical)	HCPCS C2644 Brachytherapy source, cesium-131 chloride solution, per millicurie	Device
Animal Drug	SPL 3cc46410-1360-43ba-af4f-fd33c9bc3533 THYROID SOOTHE - chamomilla, iodium, lycopus, nux vom, zingiber spray	Drug
Cellular Therapy	RxNorm 1000596 autologous cultured chondrocytes 30000000 CELLS/ML Injectable Solution [Carticel]	Drug
Implant (drug eluding)	HCPCS J7311 Fluocinolone acetonide, intravitreal implant	Drug
Procedure Drug	HCPSC J2704 Injection, propofol, 10 mg	Drug
Cytogenetic study	CPT4 88271 Molecular cytogenetics; DNA probe, each (eg, FISH)	Measurement
Cytopathology	CPT4 1012386 Cytopathology smears, cervical or vaginal	Measurement
Drug testing	HCPCS G6030 Amitriptyline (Assay of amitriptyline)	Measurement
Electrocardiogram	HCPCS G0403 Electrocardiogram, routine ecg with 12 leads; performed as a screening for the initial preventive physical examination with interpretation and report	Measurement
Hearing test	CPT4 92563 Hearing test using earphones	Measurement
Immunological test procedure	CPT4 95065 Direct nasal mucous membrane test	Measurement
Semen analysis	HCPCS G0027 Semen analysis; presence and/or motility of sperm excluding huhner	Measurement
Cosmetic	SPL 8491b3d2-1edc-4694-adf7-b9649edb00eb ONWARD CHAPSTICK - lipstick	Observation
Evaluation or assessment	HCPCS G8930 Assessment of depression severity at the initial evaluation	Observation
Lifestyle choice	ICD10 Z58.7 Exposure to tobacco smoke	Observation
Pathology report	HCPCS G9428 Pathology report includes the pt category and a statement on thickness and ulceration and for pt1, mitotic raten	Observation
Service without exact procedure	HCPCS H0030 Behavioral health hotline service, HCPCS H2016 Comprehensive community support services, per diem	Observation
Visit without procedure	HCPCS S9127 Social work visit, in the home, per diem	Observation
Anything called *ectomy	HCPCS S2350 Diskectomy, anterior, with decompression of spinal cord and/or nerve root(s), including osteophytectomy; lumbar, single interspace except some devices having *ectomy in description like HCPCS L8020 Breast prosthesis, mastectomy form	Procedure
Anything called *graphy	HCPCS C9733 Non-ophthalmic fluorescent vascular angiography	Procedure
Anything called *scopy	HCPCS S2070 Cystourethroscopy, with ureteroscopy and/or pyeloscopy; with endoscopic laser treatment of ureteral calculi (includes ureteral catheterization)	Procedure
Attention	ICD10 Z43.5 Attention to Cyctostomy	Procedure
Brachytherapy	HCPCS G0458 Low dose rate (ldr) prostate brachytherapy services, composite rate	Procedure
Counseling	HCPCS H0005 Alcohol and/or drug services; group counseling by a clinician	Procedure
Detoxification	HCPCS H0009 Alcohol and/or drug services; acute detoxification (hospital inpatient)	Procedure
Examination	ICD10 Z01.0 Examination of eyes and vision	Procedure
Imaging	CPT4 91110 Gastrointestinal tract imaging, intraluminal (eg, capsule endoscopy), esophagus through ileum, with interpretation and report	Procedure
Immunotherapy	CPT4 95115 Professional services for allergen immunotherapy not including the provision of allergenic extracts; single injection	Procedure
Management	ICD10 Z30.9 Contraceptive management, unspecified	Procedure
Monitoring	HCPCS 59050 Fetal monitoring during labor by consulting physician (ie, non-attending physician) with written report; supervision and interpretation	Procedure
Physician consult	CPT4 1014276 Pathology consultation during surgery	Procedure
Procedure Drug (without exact drug information and no RxNorm mapping)	HCPCS J8498 Antiemetic drug, rectal/suppository, not otherwise specified	Procedure
Service with exact procedure	HCPCS H0005 Alcohol and/or drug services; group counseling by a clinician	Procedure
Surgical pathology (gross or microscopic)	CPT4 88300 Level I - Surgical pathology, gross examination only	Procedure
Visit with exact procedure	HCPCS S9097 Home visit for wound care	Procedure

List of Domains

• Condition
• Currency
• Device
• Drug
• Ethnicity
• Gender
• Measurement
• Measurement Value
• Measurement Value Operator
• Metadata
• Modifier
• Observation
• Place of Service
• Procedure
• Provider Specialty
• Race
• Relationship
• Revenue Code
• Route of Administration
• Specimen
• Specimen Anatomic Site
• Specimen Disease Status
• Type Concept
• Unit
• Visit
• Combination Domains