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CDR3 length as proportion instead of clonotype number #413

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Hammer-Q opened this issue Aug 6, 2024 · 0 comments
Open

CDR3 length as proportion instead of clonotype number #413

Hammer-Q opened this issue Aug 6, 2024 · 0 comments

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@Hammer-Q
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Hammer-Q commented Aug 6, 2024

Hi all, thanks for the great package, I'm enjoying it a lot!
It might be a quite naive question: is there a possibility to analyze CDR3 lengths as a proportion/frequency instead as clonotype number?
I have a set of samples with varying clone numbers and different clonotype proportions (some highly expanded clonotypes) and think that it could be useful to display the y-axis as proportion. Is this possible?

Small edit: I guess what I am trying to generate is a CDR3 length distribution plot that is weighted for clonotype size, i.e. that highly expanded clonotypes contribute more to the distribution compared to clonotypes of small proportion. Does that make sense?

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